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Blood test of lactic acidosis
Lactic acidosis is caused by high levels of lactic acid (lactate) and protons in the bodily secretions and is usually associated with poor clinical outcomes. The intensity and clinical setting of lactic acidosis influence its impact. Lactic acid, a carbohydrate metabolism intermediate, is mostly produced by white skeletal muscle, the …
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alpha-Thalassemia
Thalassemia is a group of genetic conditions wherein defects in one or more globin genes generate reduced or insufficient production of the associated globin chains. Patients with minor genetic abnormalities are usually asymptomatic. Patients with more severe abnormalities have symptoms caused by one or more of the following: low formation …
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Smartphone app can vibrate a drop of blood to evaluate its clotting efficiency
A blood clot arises as a result of any injury to the body tissues. Blood clots, on the other hand, can trigger severe complications like strokes or MI in heart related dysfunction. Anticoagulants such as aspirin or warfarin are often administered for life as prophylaxis. These medications reduce clot formation …
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Why measure serum TMAO level?
Trimethylamine N-oxide (TMAO) has a molecular mass of 75.1 daltons and belongs to the family of amine oxides. It is commonly found in the tissues of a wide range of marine creatures, particularly marine elasmobranchs, where TMAO is known to protect against the negative effects of temperature, salinity, high urea, …
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Atherosclerosis
Atherosclerosis, also known as coronary artery disease (CAD), is the most common type of cardiovascular disease (CVD), with the main component being lipid accumulation and inflammation of the large arteries, which can eventually lead to clinical complications such as myocardial infarction (MI) and stroke. Clinically significant atherosclerosis is a slow-progressing …