Minimum Information Necessary for Quantitative Real-Time PCR Experiments

The MIQE (minimum information for the publication of quantitative real-time PCR) guidelines reflect a significant milestone for the transition of a robust “gold standard” in the process of turning the accurate quantitative polymerase chain reaction (qPCR) from a testing technique into real-time quantitative polymerase reaction (QPCR). It has allowed legacy …

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Types of Biosafety Levels

The control of potentially dangerous biological agents is an imperative goal of every biosafety system. In the sense in which infectious products are treated or preserved in the lab setting, the word “containment” is used to describe protection procedures, structures and facilities. Containment is designed to minimize or avoid access …

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Prenatal Diagnosis and Screening

Prenatal diagnostic and screening are meant to inform pregnant women and their partners to their fetus’s likelihood of birth abnormalities or genetic disorders, as well as give them with information about how to deal with the ambiguity. Many families that are known to be at high risk of having a …

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Antimicrobial mechanism of action

Introduction Clinically effective antimicrobial agents exhibit selective toxicity towards the microbe rather than the host, a feature which distinguishes them from the disinfectants. Selectivity is described in most cases by action on microbial processes or structures which differ from those of mammalian cells. For eg, some agents operate on synthesis …

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Pathogenesis of COVID-19

Coronaviruses (CoVs) are a community of Nidovirales viruses that includes the Coronaviridae, Arteriviridae, Mesoniviridae, and Roniviridae families. CoVs are members of the Coronavirinae subfamily of the Coronaviridae family of the order Nidovirales, which consists of four genera: Alphacoronavirus, Betacoronavirus, Gammacoronavirus, and Deltacoronavirus. Viruses belonging to the Nidovirales order and are …

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Immune (Idiopathic) Thrombocytopenic Purpura

Primary immune thrombocytopenia, commonly known as idiopathic thrombocytopenic purpura(ITP), is an inflammatory bleeding disorder that affects both adults and infants. It was previously thought to be an autoantibody condition in which the reticuloendothelial system prematurely destroyed platelets that had been opsonized with antiplatelet antibody. Recent studies have revealed that there …

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