Clinical Pathology

Types of Laboratory grade water

Types of Laboratory grade water

Water quality is considered by many laboratorians to be one of the most important preanalytical variables that impacts laboratory testing. Many people believe water to be a laboratory reagent, and it’s used to make buffers, blanks, calibrators, controls, mobile phase, reaction mixtures, and reagent reconstitution for a variety of lab tests. As a result, using…

Factors interfering analytic tests

Factors interfering analytic tests

As a result of interfering factors, test results might be affected. When it comes to interference factors, it relies on the method adopted to analyze the same analyte. Hemolysis, lipemia, icterus, drugs, paraproteins, and other sample contaminants, such as gels, tube additives, and fibrin clots, are all examples of interference factors that might occur. A…

Anti-CCP

Anti-CCP

Rheumatoid Arthritis (RA) is the most prevalent inflammatory joint disease, affecting roughly 1% of the global adult population. It is characterized by persistent synovial inflammation, which frequently leads to progressive joint degeneration, disability, and a loss in quality of life. Although the exact cause of RA is unknown, autoimmunity is strongly linked to the illness,…

Cerebrospinal fluid (CSF)

Cerebrospinal fluid (CSF)

The cerebrospinal fluid (CSF) was first identified by Cotugno in 1764, which is a major body fluid. CSF provides a systemic mechanism for providing nutrients to the nervous tissue, eliminating metabolic waste and building a structural shield against damage to protect the brain and spinal cord. The meninges cover the brain and spinal cord, consisting…

Semen Analysis

Semen Analysis

Introduction The testes, epididymis, seminal tubes, prostate, and bulbourethral glands are among the four fractions of sperm. Since the composition of the tis differs with increasing fraction, combining all four fractions during ejaculation is needed to obtain a good semen specimen. Composition of semen Spermatozoa:    5% Seminal Fluid:    60% – 70% Prostate fluid:…

Fecal occult blood test

Fecal occult blood test

The fecal occult blood test detects bleeding in the gastrointestinal tract in a simple, fast, and low-cost manner. Although the treatment is not definitive for colorectal cancer or any other disease, it is commonly used as a colorectal cancer screening test, and is a leading cause of cancer death. When malignant or cancerous cells develop…