WNT signaling pathway
The WNT signaling pathway was first discovered in colon cancer research and embryonic development studies of fruit flies (Drosophila melanogaster), frogs (Xenopus laevis), and other animals. Colorectal and other forms of cancers may be caused by abnormal activation of the WNT pathway. The bipartite transcription factor β-catenin/ Tcell factor (β-cat/TCF) …