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clinicalsci

A tech enthusiast medical molecular technologist, biotechnologist and now also a blogger.

Double Immunodiffusion

Immunodiffusion Assays involving the diffusion of soluble antigen and antibody include the precipitation reaction. When the concentrations reach a critical point, a visible precipitate is formed, which is made up of an insoluble complex of antigens and antibodies. In an…

Cystic Fibrosis

Cystic Fibrosis is a multi-system disease marked by a monogenic condition. While Cystic Fibrosis is mostly a childhood condition, about 5% of adults are diagnosed with it. About 41% of Cystic Fibrosis patients are over the age of 18, and…

WNT signaling pathway

The WNT signaling pathway was first discovered in colon cancer research and embryonic development studies of fruit flies (Drosophila melanogaster), frogs (Xenopus laevis), and other animals. Colorectal and other forms of cancers may be caused by abnormal activation of the…

Entamoeba histolytica

Amebic colitis, amebic dysentery, and extraintestinal amebiasis are some of common disease or disorder names. Humans are infected by this ameba. It can cause flask-shaped lesions and bloody diarrhea by infecting the mucosa of the colon.The trophozoite secretes lyticenzymes, which…

Pelger-Huët Anomaly

Pelger-Huët anomaly (PHA), also known as true or congenital PHA, is an autosomal dominant condition marked by reduced nuclear segmentation (bilobed, unilobed) and a distinctive coarse chromatin clumping pattern that can involve any leukocyte, while morphologic differences are more noticeable…

Catalase Test

PRINCIPLE Bacteria that produce the enzyme catalase break down hydrogen peroxide into water and gaseous oxygen, allowing gas bubbles to escape. Most bacteria can be identified using this test. REAGENTS AND SUPPLIES A.Hydrogen peroxide reagent 30% For Neisseria30 percent H2O2…